A LINEAR-TIME ALGORITHM FOR CALCULATION OF MULTIPLE PAIRWISE KINSHIP COEFFICIENTS AND THE GENETIC INDEX OF FAMILIALITY

被引:7
作者
GHOLAMI, K
THOMAS, A
机构
[1] UNIV BATH,SCH MATH SCI,BATH BA2 7AY,AVON,ENGLAND
[2] DEPT MED INFORMAT,SALT LAKE CITY,UT 84108
来源
COMPUTERS AND BIOMEDICAL RESEARCH | 1994年 / 27卷 / 05期
关键词
D O I
10.1006/cbmr.1994.1026
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
We present an algorithm that calculates the mean kinship coefficient between all pairs of individuals in a given set relative to a known pedigree. The time required to make the calculations is proportional to the size of the set. The constant of proportionality is determined by the number of generations that the pedigree spans. A simple alteration to the algorithm allows efficient calculation of all pairwise kinship coefficients within a set of individuals. (C) 1994 Academic Press, Inc.
引用
收藏
页码:342 / 350
页数:9
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