ENHANCED FLUORESCENCE IN THE BINDING OF OLIGONUCLEOTIDES WITH A PYRENE GROUP IN THE SUGAR FRAGMENT TO COMPLEMENTARY POLYNUCLEOTIDES

被引：49

作者：

YAMANA, K ^{[1
]}

GOKOTA, T ^{[1
]}

OZAKI, H ^{[1
]}

NAKANO, H ^{[1
]}

SANGEN, O ^{[1
]}

SHIMIDZU, T ^{[1
]}

机构：

[1] KYOTO UNIV,GRAD SCH ENGN,DIV MOLEC ENGN,SAKYO KU,KYOTO 606,JAPAN

来源：

NUCLEOSIDES & NUCLEOTIDES | 1992年 / 11卷 / 2-4期

关键词：

D O I：

10.1080/07328319208021712

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The fluorescence intensity and lifetime of oligonucleotides with a pyrenylmethyl group at the specific sugar residue were increased upon binding to their complementary polynucleotide in aqueous solution. The present oligonucleotide-pyrene conjugates provide new fluorescent probes for detection of specific nucleic acids.

引用

页码：383 / 390

页数：8

共 13 条

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