LUTEINIZING-HORMONE PULSATILE RELEASE AND THE LENGTH OF LACTATIONAL AMENORRHEA

被引：3

作者：

DIAZ, S ^{[1
]}

CARDENAS, H ^{[1
]}

ZEPEDA, A ^{[1
]}

BRANDEIS, A ^{[1
]}

SCHIAPPACASSE, V ^{[1
]}

MIRANDA, P ^{[1
]}

SERONFERRE, M ^{[1
]}

CROXATTO, HB ^{[1
]}

机构：

[1] INST CHILENO MED REPROD,SANTIAGO,CHILE

来源：

HUMAN REPRODUCTION | 1995年 / 10卷 / 08期

关键词：

BREAST-FEEDING; LACTATIONAL AMENORRHEA; LUTEINIZING HORMONE PULSES; POSTPARTUM;

D O I：

10.1093/oxfordjournals.humrep.a136216

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The pattern of luteinizing hormone (LH) pulsatile release and the mean concentrations of follicle-stimulating hormone, oestradiol and progesterone were studied in nursing and non-nursing women. Blood samples were drawn at 5 min intervals between 10:00 and 14:00 h and between 22:00 and 02:00 h at months 3-4, 5-6, 7-8 and 9-10 post-partum in nursing women and in the follicular phase in non-nursing women. In nursing women, mean LH concentrations at months 3-4 were significantly lower than in non-nursing cycling women only in the subgroup which subsequently experienced >6 months of lactational amenorrhoea, although all were fully nursing with a similar suckling frequency. LH pulses in plasma were found at all times in nursing women. There were no significant differences in the frequency (about four pulses every 4 h), amplitude or duration of LH pulses related to the duration of amenorrhoea, nor did these parameters vary significantly between amenorrhoeic or cycling nursing women and nonnursing women. Nursing amenorrhoeic women exhibited a normal frequency of LH pulse well in advance of the resumption of the first post-partum menses, suggesting that mechanisms other than the suppression of the gonadotrophin-releasing hormone pulse generator intervened in the inhibition of ovarian function during lactation.

引用

页码：1957 / 1961

页数：5

共 26 条

[1] PROLACTIN BIOACTIVITY AND THE DURATION OF LACTATIONAL AMENORRHEA [J].