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FLOW CYTOMETRIC DNA HISTOGRAMS OF PARAFFIN-EMBEDDED PHEOCHROMOCYTOMAS
被引：5
作者：
HOSAKA, Y
ASO, Y
RAINWATER, LM
GRANT, CS
FARROW, GM
VANHEERDEN, JA
LIEBER, MM
机构：
关键词：
PHEOCHROMOCYTOMA;
FLOW CYTOMETRY;
DNA HISTOGRAM;
PARAFFIN-EMBEDDED SPECIMEN;
D O I：
10.1159/000282264
中图分类号：
R5 [内科学];
R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ;
100201 ;
摘要：
We proposed a new classification of pheochromocytomas according to DNA ploidy patterns. Proliferation index (PI = S% + 4C%) might be an alternative to 4C% which was used as a critical marker of DNA nonaneuploid histograms. The follow-up survey revealed that DNA tetraploid with minimum increase of PI could not rule out the substantial possibility of malignancy and the comparison of DNA diploid histograms disclosed that 22 and 0% showed significant increase of the ratio of 4C% to S% under PI and 4C% criteria, respectively. In conclusion, 4C% was more effective and reliable than PI in order to classify DNA nonaneuploid pheochromocytomas.
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页码：100 / 103
页数：4
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