LACK OF BACTERICIDAL EFFECT OF ANTIBIOTICS EXCEPT AMINOGLYCOSIDES ON BARTONELLA (ROCHALIMAEA) HENSELAE

被引：66

作者：

MUSSO, D ^{[1
]}

DRANCOURT, M ^{[1
]}

RAOULT, D ^{[1
]}

机构：

[1] FAC MED MARSEILLE,UNITE RICETTSIES,F-13385 MARSEILLE 05,FRANCE

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1995年 / 36卷 / 01期

关键词：

D O I：

10.1093/jac/36.1.101

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Bartonella (Rochalimaea) henselae is a cause of peliosis hepatis and bacillary angiomatosis, and one of the putative agents of cat scratch disease. Specific therapy for B. henselae infections is not available. Treatment failures and relapses are frequent, especially following brief antibiotic courses, and this contrasts with the in-vitro susceptibility of B. henselae to most antibiotics. We decided to test the antibiotic susceptibility of B. henselae associated with murine macrophage-like cells (P388 D-l) and a human endothelial cell line. We carried out a bactericidal assay in this model and in axenic broth. In both models, only aminoglycosides were bactericidal. These results suggest that aminoglycosides may be effective in the treatment of B. henselae infections.

引用

页码：101 / 108

页数：8

共 35 条

[1]

Acar J. F., 1991, ANTIBIOTICS LAB MED, P17

[2] EIA FOR DETECTION OF ROCHALIMAEA-HENSELAE - REACTIVE IGG, IGM, AND IGA ANTIBODIES IN PATIENTS WITH SUSPECTED CAT-SCRATCH DISEASE [J].

BARKA, NE ;

HADFIELD, T ;

PATNAIK, M ;

SCHWARTZMAN, WA ;

PETER, JB .

JOURNAL OF INFECTIOUS DISEASES, 1993, 167 (06) :1503-1504

[3] BACILLARY (EPITHELIOID) ANGIOMATOSIS AND CONCURRENT KAPOSIS SARCOMA IN ACQUIRED IMMUNODEFICIENCY SYNDROME [J].

BERGER, TG ;

TAPPERO, JW ;

KAYMEN, A ;

LEBOIT, PE .

ARCHIVES OF DERMATOLOGY, 1989, 125 (11) :1543-1547

[4] ANTIBIOTIC-THERAPY FOR CAT-SCRATCH DISEASE [J].

BOGUE, CW ;

WISE, JD ;

GRAY, GF ;

EDWARDS, KM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1989, 262 (06) :813-816

[5] PROPOSALS TO UNIFY THE GENERA BARTONELLA AND ROCHALIMAEA, WITH DESCRIPTIONS OF BARTONELLA-QUINTANA COMB-NOV, BARTONELLA-VINSONII COMB-NOV, BARTONELLA-HENSELAE COMB-NOV, AND BARTONELLA-ELIZABETHAE COMB-NOV, AND TO REMOVE THE FAMILY BARTONELLACEAE FROM THE ORDER RICKETTSIALES [J].

BRENNER, DJ ;

OCONNOR, SP ;

WINKLER, HH ;

STEIGERWALT, AG .

INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, 1993, 43 (04) :777-786

[6] BACILLARY EPITHELIOID ANGIOMATOSIS OCCURRING IN AN IMMUNOCOMPETENT INDIVIDUAL [J].

COCKERELL, CJ ;

BERGSTRESSER, PR ;

MYRIEWILLIAMS, C ;

TIERNO, PM .

ARCHIVES OF DERMATOLOGY, 1990, 126 (06) :787-790

[7] CAT-SCRATCH DISEASE - ISOLATION AND CULTURE OF THE BACTERIAL AGENT [J].

ENGLISH, CK ;

WEAR, DJ ;

MARGILETH, AM ;

LISSNER, CR ;

WALSH, GP .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1988, 259 (09) :1347-1352

[8] FIBROBLASTS PROTECT THE LYME-DISEASE SPIROCHETE, BORRELIA-BURGDORFERI, FROM CEFTRIAXONE INVITRO [J].

GEORGILIS, K ;

PEACOCKE, M ;

KLEMPNER, MS .

JOURNAL OF INFECTIOUS DISEASES, 1992, 166 (02) :440-444

[9] ENDOCARDITIS CAUSED BY ROCHALIMAEA-HENSELAE [J].

HADFIELD, TL ;

WARREN, R ;

KASS, M ;

BRUN, E ;

LEVY, C .

HUMAN PATHOLOGY, 1993, 24 (10) :1140-1141

[10] VISCERAL BACILLARY EPITHELIOID ANGIOMATOSIS - POSSIBLE MANIFESTATIONS OF DISSEMINATED CAT SCRATCH DISEASE IN THE IMMUNOCOMPROMISED HOST - A REPORT OF 2 CASES [J].

KEMPER, CA ;

LOMBARD, CM ;

DERESINSKI, SC ;

TOMPKINS, LS .

AMERICAN JOURNAL OF MEDICINE, 1990, 89 (02) :216-222

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