DIASTEREOSELECTIVE TOTAL SYNTHESES OF (+/-)-TRIPTOQUINONE-B AND TRIPTOQUINONE-C

被引：8

作者：

SHISHIDO, K

GOTO, K

TSUDA, A

TAKAISHI, Y

SHIBUYA, M

机构：

[1] OTSUKA PHARMACEUT FACTORY INC,NEW DRUG RES LAB,NARUTO,TOKUSHIMA 772,JAPAN

[2] UNIV TOKUSHIMA,FAC PHARMACEUT SCI,TOKUSHIMA 770,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1993年 / 09期

关键词：

D O I：

10.1039/c39930000793

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first and efficient total syntheses of (+/-)-triptoquinone B 1 and C2 have been achieved from the allyl ether3; the key steps are the construction of the four contiguous stereogenic centres present in 2 by the Mn(III) mediated oxidative free radical cyclisation followed by metal hydride reduction.

引用

页码：793 / 794

页数：2

共 6 条

[1]

BURNELL RH, 1990, SYNTHETIC COMMUN, V20, P2469

[2]

PETRANEK J, 1970, COLLECT CZECH CHEM C, V35, P380

[3]

SHIBUYA M, 1992, Patent No. 211035

[4] MANGANESE(III)-BASED OXIDATIVE FREE-RADICAL CYCLIZATION - SYNTHESIS OF (+/-)-PODOCARPIC ACID [J].