Endogenous morphine

被引：8

作者：

Hosztafi, S ^{[1
]}

Furst, Z ^{[1
]}

机构：

[1] SEMMELWEIS UNIV MED,DEPT PHARMACOL,H-1445 BUDAPEST,HUNGARY

来源：

PHARMACOLOGICAL RESEARCH | 1995年 / 32卷 / 1-2期

关键词：

endogenous opioids; mammalian morphine; morphine biosynthesis; alcohol and formation of endogenous morphine; role of endogenous alkaloids;

D O I：

10.1016/S1043-6618(95)80003-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This review surveys the discovery of endogenous alkaloids in mammals. The formation of morphine in mammalian brain was assumed in 1970. The existence of morphine was demonstrated by radioimmunoassay. Identification of morphine was performed by spectroscopic methods. The isolation of mammalian morphine raises the question of biosynthesis. Recently, it has been shown that the biosynthetic pathway is similar to that that exists in poppy. (C) 1995 The Italian Pharmacological Society

引用

页码：15 / 20

页数：6

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