IMMUNOHISTOCHEMICAL STUDY OF GRANULAR-CELL TUMORS OF THE NEUROHYPOPHYSIS

被引：35

作者：

NISHIOKA, H ^{[1
]}

II, K ^{[1
]}

LLENA, JF ^{[1
]}

HIRANO, A ^{[1
]}

机构：

[1] MONTEFIORE MED CTR,DEPT PATHOL,DIV NEUROPATHOL,BLUESTONE LAB,111 E 210TH ST,BRONX,NY 10467

来源：

VIRCHOWS ARCHIV B-CELL PATHOLOGY INCLUDING MOLECULAR PATHOLOGY | 1991年 / 60卷 / 06期

关键词：

NEUROHYPOPHYSIS; GRANULAR CELL TUMOR; IMMUNOHISTOCHEMISTRY; CATHEPSIN-B; PITUICYTE;

D O I：

10.1007/BF02899574

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Six granular cell tumors (GCT) of the neurohypophysis were studied by immunohistochemical techniques. They were all labeled by peanut lectin (Arachis hypogaea) and three showed reactivity for S-100 protein. Unlike extracranial GCT, neuron specific enolase (NSE), myelin basic protein (MBP) and vimentin were not detected in the tumor cells. Glial fibrillary acidic protein (GFAP), keratin and desmin were also not observed. On the other hand, some showed reactivity for alpha-1-antitrypsin (AAT), alpha-1-antichymotrypsin (AAC) and cathepsin B. These results suggest that neurohypophysial GCT have some features different from extracranial GCT and that they may not be derived from Schwann cells.

引用

页码：413 / 417

页数：5

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