P300 AUDITORY EVENT-RELATED POTENTIALS IN NONTRAUMATIC COMA - ASSOCIATION WITH GLASGOW COMA SCORE AND AWAKENING

被引：64

作者：

GOTT, PS ^{[1
]}

RABINOWICZ, AL ^{[1
]}

DEGIORGIO, CM ^{[1
]}

机构：

[1] UNIV SO CALIF,MED CTR,EEG EVOKED POTENTIAL LAB,LOS ANGELES,CA 90089

来源：

ARCHIVES OF NEUROLOGY | 1991年 / 48卷 / 12期

关键词：

D O I：

10.1001/archneur.1991.00530240071024

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Auditory event-related potentials (ERPs) were performed in 20 patients with nontraumatic coma to determine the presence of a P300 ERP in coma and its association with the Glasgow Coma Score and awakening (Glasgow Outcome Score, greater-than-or-equal-to 3). A standard "oddball" paradigm was used: frequent tone, 1 kHz; rare tone, 2 kHz and 4 Hz; probability, 20%. The Glasgow Coma Score was determined concurrently with the P300 ERP. Thirty percent (6/20) of the comatose patients had a P300 ERP. The mean Glasgow Coma Score was significantly higher for those with a P300 ERP. Eighty-three percent (5/6) of those with a P300 ERP awoke. Presence of a P300 ERP was associated significantly with awakening, but absence of a P300 ERP did not preclude it.

引用

页码：1267 / 1270

页数：4

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