BIS-BASIC-SUBSTITUTED POLYCYCLIC AROMATIC-COMPOUNDS - NEW CLASS OF ANTIVIRAL AGENTS .2. TILORONE AND RELATED BIS-BASIC ETHERS OF FLUORENONE, FLUORENOL, AND FLUORENE

被引：78

作者：

ANDREWS, ER ^{[1
]}

FLEMING, RW ^{[1
]}

GRISAR, JM ^{[1
]}

KIHM, JC ^{[1
]}

WENSTRUP, DL ^{[1
]}

MAYER, GD ^{[1
]}

机构：

[1] MERRELL NATL LABS,CINCINNATI,OH 45215

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1974年 / 17卷 / 08期

关键词：

D O I：

10.1021/jm00254a020

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：882 / 886

页数：5

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共 29 条

[1] ADAMSON RH, 1971, J NATL CANCER I, V46, P431
[2] FLUORENE DERIVATIVES FOR ANTITUMOR ACTIVITY
AGRAWAL, KC
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1967, 10 (01) : 99 - &
[3] ALBRECHT WL, 1972, 13 NAT MED CHEM S AM
[4] 3-6-DISUBSTITUTED FLUORENES .2. THE PREPARATION OF 3-6-DIAMINOFLUORENE FROM FLUORENE, AND THE ATTEMPTED INTERNUCLEAR CYCLISATION OF DERIVATIVES OF 4-4'-DIAMINODIPHENYLMETHANE
BARKER, A
BARKER, CC
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1954, (MAR): : 870 - 873
[5] BARKER AD, 1971, P SOC EXP BIOL MED, V137, P981
[6] BIS-DEAE-FLUORENONE - A SPECIFIC INHIBITOR OF DNA POLYMERASES FROM RNA TUMOR VIRUSES
CHANDRA, P
ZUNINO, F
GOTZ, A
[J]. FEBS LETTERS, 1972, 22 (02) : 161 - &
[7] Courtot C, 1930, ANN CHIM FRANCE, V14, P5
[8] Courtot C, 1925, CR HEBD ACAD SCI, V180, P1665
[9] BIS-DEAE-FLUORENONE - MECHANISM OF ANTIVIRAL PROTECTION AND STIMULATION OF INTERFERON PRODUCTION IN MOUSE
DECLERCQ, E
MERIGAN, TC
[J]. JOURNAL OF INFECTIOUS DISEASES, 1971, 123 (02) : 190 - &
[10] TILORONE HYDROCHLORIDE - LACK OF CORRELATION BETWEEN INTERFERON INDUCTION AND VIRAL PROTECTION
GIRON, DJ
SCHMIDT, JP
PINDAK, FF
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1972, 1 (01) : 78 - &