5Q DELETION - THE SOLE CHROMOSOME CHANGE IN A CARCINOMA OF THE BLADDER

Direct chromosome preparations of a transitional cell carcinoma of the bladder that had invaded the mucosa but not more deeply showed a 46,XY,5q- karyotype in nearly all metaphases. This is the first description of a 5q deletion, which may have been interstitial, del(5)(q13q22), as the only change in a bladder carcinoma. © 1990.