A NEW-TYPE OF CYTOTOXIC ANNONACEOUS ACETOGENIN - GIGANIN FROM GONIOTHALAMUS-GIGANTEUS

被引：22

作者：

FANG, XP ^{[1
]}

SONG, R ^{[1
]}

GU, ZM ^{[1
]}

RIESER, MJ ^{[1
]}

MIESBAUER, LR ^{[1
]}

SMITH, DL ^{[1
]}

MCLAUGHLIN, JL ^{[1
]}

机构：

[1] PURDUE UNIV,SCH PHARM & PHARMACAL SCI,DEPT MED CHEM & PHARMACOGNOSY,W LAFAYETTE,IN 47907

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 06期

关键词：

D O I：

10.1016/S0960-894X(00)80305-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new cytotoxic Annonaceous acetogenin, giganin (1), was isolated from the bark of Goniothalamus giganteus (Annonaceae). This compound represents a new type of Annonaceous acetogenin lacking tetrahydrofuran or epoxide rings along the aliphatic chain, and its structure was elucidated by H-1 and C-13 NMR, MS, COSY, and single-relayed COSY.

引用

页码：1153 / 1156

页数：4

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