FINGERPRINTING AND ACTIVITY OF SULPHA DRUGS IN SURFACE-ENHANCED RAMAN-SPECTROMETRY ON SILVER HYDROSOLS

被引：13

作者：

MONTES, R ^{[1
]}

LASERNA, JJ ^{[1
]}

机构：

[1] UNIV MALAGA,FAC SCI,DEPT ANALYT CHEM,E-29071 MALAGA,SPAIN

来源：

ANALYST | 1990年 / 115卷 / 12期

关键词：

SURFACE-ENHANCED RAMAN SPECTROMETRY; COLLOIDAL SILVER SUBSTRATE; SULPHA DRUG;

D O I：

10.1039/an9901501601

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Surface-enhanced Raman spectrometry (SERS) of sulpha drugs on silver hydrosols is reported. The SERS active substrate, colloidal silver, was prepared by reduction of silver nitrate with sodium tetrahydroborate(III) at room temperature. Detection of trace amounts of the drugs was possible because of the presence of the sulphonamide group in the molecule. However, substituents near the sulphonamide group were shown to have a significant effect on the detectability of a given drug. The selectivity of SERS as an analytical technique is illustrated.

引用

页码：1601 / 1605

页数：5

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