SYNTHESIS OF COMBRETASTATIN D-2+

被引：45

作者：

DESHPANDE, VH

GOKHALE, NJ

机构：

[1] National Chemical Laboratory, Pune

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 29期

关键词：

D O I：

10.1016/S0040-4039(00)74692-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of combretastatin D-2 methyl ether (2) by macrolactonization of hydroxy acid 11 under modified Mitsunobu conditions is described. In accord with the literature, attempts to cyclize 11 via various conventional macrolactonization methods failed.

引用

页码：4213 / 4216

页数：4

共 13 条

[1] TOTAL SYNTHESIS OF COMBRETASTATIN D-2 - INTRAMOLECULAR ULLMANN MACROCYCLIZATION REACTION
BOGER, DL
SAKYA, SM
YOHANNES, D
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (13) : 4204 - 4207
[2] A SIMPLE SHORT SYNTHESIS OF ISOTACHIN-C
DESHMUKH, ARAS
JOSHI, GD
GORE, KG
KULKARNI, GH
[J]. SYNTHETIC COMMUNICATIONS, 1990, 20 (15) : 2259 - 2265
[3] HANAOKA M, 1973, TETRAHEDRON LETT, P2355
[4] ESTER SYNTHESIS WITH DICYCLOHEXYLCARBODIIMIDE IMPROVED BY ACID CATALYSTS
HOLMBERG, K
HANSEN, B
[J]. ACTA CHEMICA SCANDINAVICA SERIES B-ORGANIC CHEMISTRY AND BIOCHEMISTRY, 1979, 33 (06): : 410 - 412
[5] RAPID ESTERIFICATION BY MEANS OF MIXED ANHYDRIDE AND ITS APPLICATION TO LARGE-RING LACTONIZATION
INANAGA, J
HIRATA, K
SAEKI, H
KATSUKI, T
YAMAGUCHI, M
[J]. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1979, 52 (07) : 1989 - 1993
[6] ITOKAWA H, 1986, CHEM PHARM BULL, V34, P3762
[7] 1ST SYNTHESIS OF A STRAINED 14-MEMBERED BIARYL ETHER LACTONE BY MACROLACTONIZATION
JUSTUS, K
STEGLICH, W
[J]. TETRAHEDRON LETTERS, 1991, 32 (41) : 5781 - 5784
[8] 4-DIALKYLAMINOPYRIDINES AS ACYLATION CATALYSTS .5. SIMPLE METHOD FOR ESTERIFICATION OF CARBOXYLIC-ACIDS
NEISES, B
STEGLICH, W
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1978, 17 (07): : 522 - 524
[9] ANTINEOPLASTIC AGENTS .160. ISOLATION AND STRUCTURE OF COMBRETASTATIN-D-1 - A CELL-GROWTH INHIBITORY MACROCYCLIC LACTONE FROM COMBRETUM-CAFFRUM
PETTIT, GR
SINGH, SB
NIVEN, ML
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (25) : 8539 - 8540
[10] OF4949, NEW INHIBITORS OF AMINOPEPTIDASE-B .2. ELUCIDATION OF STRUCTURE
SANO, S
IKAI, K
KATAYAMA, K
TAKESAKO, K
NAKAMURA, T
OBAYASHI, A
EZURE, Y
ENOMOTO, H
[J]. JOURNAL OF ANTIBIOTICS, 1986, 39 (12) : 1685 - 1696

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