CALCITRIOL PULSE THERAPY FOR SEVERE HYPERPARATHYROIDISM OR CALCIUM SALTS AS PHOSPHATE BINDERS IN RENAL DIALYSIS PATIENTS

被引：8

作者：

GONELLA, M ^{[1
]}

CALABRESE, G ^{[1
]}

ALEO, AG ^{[1
]}

VAGELLI, G ^{[1
]}

DEAMBROGIO, P ^{[1
]}

机构：

[1] GEN HOSP,CLIN PATHOL LAB,I-15033 CASALE MONFERRATO,ITALY

来源：

NEPHRON | 1995年 / 71卷 / 03期

关键词：

DIALYSIS; HYPERPARATHYROIDISM; CALCITRIOL PULSE THERAPY; CACO3; DIVALENT IONS;

D O I：

10.1159/000188742

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The concurrent use of calcitriol (CAL) pulse therapy to reduce parathyroid hormone (PTH) secretion and of calcium (Ca) salts as the most appropriate phosphate binders was evaluated for over 1 year in a group of 14 patients with good divalent ion control on CaCO3 therapy but with increasing levels of serum intact PTH. CAL pulse therapy was effective and safe in only 2 patients; in the remaining subjects it resulted in hypercalcemia and/or hyperphosphatemia, not reversed by adjusting the dialysate Ca concentration and/ or CaCO3 dose, and had to be stopped. Therefore, CAL pulse therapy does not seem to be compatible with Ca salts which, in our opinion, deserve priority in the therapy of renal dialysis patients.

引用

页码：350 / 353

页数：4

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