THE DISPOSITION OF ANTIPYRINE AND ITS METABOLITES IN YOUNG AND ELDERLY HEALTHY-VOLUNTEERS

被引：44

作者：

POSNER, J

DANHOF, M

TEUNISSEN, MWE

BREIMER, DD

WHITEMAN, PD

机构：

[1] WELLCOME RES LABS, DEPT CLIN PHARMACOL, LANGLEY COURT, BECKENHAM BR3 3BS, KENT, ENGLAND

[2] STATE UNIV LEIDEN, CTR BIOPHARMACEUT SCI, DIV PHARMACOL, 2312 AV LEIDEN, NETHERLANDS

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1987年 / 24卷 / 01期

关键词：

D O I：

10.1111/j.1365-2125.1987.tb03135.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：51 / 55

页数：5

共 23 条

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[2]

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[3] DIFFERENTIAL-EFFECTS OF ENZYME-INDUCTION ON ANTIPYRINE METABOLITE FORMATION [J].

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[4] ASSAY OF ANTIPYRINE AND ITS PRIMARY METABOLITES IN PLASMA, SALIVA AND URINE BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY AND SOME PRELIMINARY-RESULTS IN MAN [J].

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BREIMER, DD .

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[5] STUDIES ON THE DIFFERENT METABOLIC PATHWAYS OF ANTIPYRINE IN MAN .1. ORAL-ADMINISTRATION OF 250, 500 AND 1000 MG TO HEALTHY-VOLUNTEERS [J].

DANHOF, M ;

BREIMER, DD .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1979, 8 (06) :529-537

[6] HEPATIC DRUG ACETYLATION AND OXIDATION - EFFECTS OF AGING IN MAN [J].

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RAWLINS, MD ;

JAMES, O .

BRITISH MEDICAL JOURNAL, 1977, 2 (6080) :155-156

[7] ASSESSMENT OF ANTIPYRINE KINETICS BY MEASUREMENT IN SALIVA [J].

FRASER, HS ;

MUCKLOW, JC ;

MURRAY, S ;

DAVIES, DS .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1976, 3 (02) :321-325

[8] CLOBAZAM KINETICS IN THE ELDERLY [J].

GREENBLATT, DJ ;

DIVOLL, M ;

PURI, SK ;

HO, I ;

ZINNY, MA ;

SHADER, RI .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1981, 12 (05) :631-636

[9]

GREENBLATT DJ, 1982, NEW ENGL J MED, V306, P1081

[10]

GREENBLATT DJ, 1979, CLIN PHARMACOL THER, V26, P103

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