QUANTIFICATION OF THE RELATION BETWEEN ELECTROPHYSIOLOGIC AND MORPHOLOGICAL-CHANGES IN EXPERIMENTAL ENDOLYMPHATIC HYDROPS

被引:27
作者
KLIS, SFL
BUIJS, J
SMOORENBURG, GF
机构
[1] Department of Otorhinolaryngology, University Hospital Utrecht, Utrecht
关键词
electrocochleography; endolymphatic hydrops; histology;
D O I
10.1177/000348949009900714
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The degree of hydrops in guinea pig ears that had undergone unilateral endolymphatic sac and duct obliteration was quantified. For 15 guinea pigs from a prior study, the correlation between the degree of hydrops and several electrophysiologic measures of the functional state of the cochlea was determined. A significant correlation between the degree of hydrops and a reduction in the low-frequency cochlear microphonic evoked by a 29-Hz tone was found. No correlation was found between the degree of hydrops and the magnitude of the summating potential evoked by 8-kHz probes. A weak correlation was found between the degree of hydrops and a reduction in the compound action potential evoked by 2-kHz probes. Possible differences in the way the endolymphatic duct obliteration exerts its effect on the different cochlear potentials are discussed. © 1990, SAGE Publications. All rights reserved.
引用
收藏
页码:566 / 570
页数:5
相关论文
共 15 条
[1]   ULTRASTRUCTURE OF THE STRIA VASCULARIS AND REISSNERS MEMBRANE IN EXPERIMENTAL HYDROPS [J].
ALBERS, FWJ ;
DEGROOT, JCMJ ;
VELDMAN, JE ;
HUIZING, EH .
ACTA OTO-LARYNGOLOGICA, 1987, 104 (3-4) :202-210
[2]   EARLY HAIR CELL LOSS IN EXPERIMENTAL HYDROPS [J].
ALBERS, FWJ ;
VELDMAN, JE ;
HUIZING, EH .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1987, 96 (03) :282-285
[3]   RAPIDLY FLUCTUATING THRESHOLDS AT THE ONSET OF EXPERIMENTALLY-INDUCED HYDROPS IN THE GUINEA-PIG [J].
HORNER, KC ;
CAZALS, Y .
HEARING RESEARCH, 1987, 26 (03) :319-325
[4]  
KIMURA RS, 1965, PRACT-OTO-RHINO-LARY, V27, P343
[5]  
KIMURA RS, 1981, MENIERES DISEASE, P15
[6]   MODULATION AT THE GUINEA-PIG ROUND WINDOW OF SUMMATING POTENTIALS AND COMPOUND ACTION-POTENTIALS BY LOW-FREQUENCY SOUND [J].
KLIS, JFL ;
SMOORENBURG, GF .
HEARING RESEARCH, 1985, 20 (01) :15-23
[7]   COCHLEAR POTENTIALS AND THEIR MODULATION BY LOW-FREQUENCY SOUND IN EARLY ENDOLYMPHATIC HYDROPS [J].
KLIS, JFL ;
SMOORENBURG, GF .
HEARING RESEARCH, 1988, 32 (2-3) :175-184
[8]   EXPERIMENTAL ENDOLYMPHATIC HYDROPS AND ITS RELIEF BY INTERRUPTING LATERAL SEMICIRCULAR DUCT IN GUINEA-PIGS [J].
KONISHI, S ;
SHEA, JJ .
JOURNAL OF LARYNGOLOGY AND OTOLOGY, 1975, 89 (06) :577-592
[9]   SACCULAR AND COCHLEAR ENDOLYMPHATIC POTENTIALS IN EXPERIMENTALLY INDUCED ENDOLYMPHATIC HYDROPS OF GUINEA-PIGS [J].
KUSAKARI, J ;
KOBAYASHI, T ;
ARAKAWA, E ;
ROKUGO, M ;
OHYAMA, K ;
INAMURA, N .
ACTA OTO-LARYNGOLOGICA, 1986, 101 (1-2) :27-33
[10]  
MORGENSTERN C, 1985, ARCH OTORHINOLARY S1, V241, P1