RESISTANCE OF PEPTOSTREPTOCOCCUS SPP TO MACROLIDES AND LINCOSAMIDES - INDUCIBLE AND CONSTITUTIVE PHENOTYPES

The activities of erythromycin and clindamycin against 350 Peptostreptococcus strains were studied during a 5-year period (1986 to 1991). In 5.1% of the Peptostreptococcus strains, which presented dissociated resistance (clindamycin MIC, less-than-or-equal-to 1-mu-g/ml; erythromycin MIC, > 8-mu-g/ml), evidence of inducible macrolide-lincosamide resistance was shown. A total of 17.7% of the strains presented a constitutive phenotype; the clindamycin and erythromycin MICs for these strains were greater than 8-mu-g/ml.