THE REGULATION OF B-LYMPHOCYTE AND T-LYMPHOCYTE ACTIVATION BY THE TRANSMEMBRANE PROTEIN-TYROSINE-PHOSPHATASE CD45

被引：44

作者：

THOMAS, ML

机构：

[1] Howard Hughes Medical Institute, Washington University School of Medicine, St. Louis, MO 63110

来源：

CURRENT OPINION IN CELL BIOLOGY | 1994年 / 6卷 / 02期

关键词：

D O I：

10.1016/0955-0674(94)90143-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The expression of transmembrane protein tyrosine phosphatase CD45 is required for antigen-induced activation of T and B lymphocytes. During the past year, advances have been made in our understanding of CD45 regulation and its role in regulating Src-family members. The importance of CD45 in thymocyte maturation has been demonstrated through the generation of CD45-knockout mice.

引用

收藏

页码：247 / 252

页数：6

相关论文

共 61 条

[1] ASSOCIATION OF CD2 AND T200 (CD45) IN MOUSE LYMPHOCYTE-T [J].

ALTEVOGT, P ;

SCHRECK, J ;

SCHRAVEN, B ;

MEUER, S ;

SCHIRRMACHER, V ;

MITSCH, A .

INTERNATIONAL IMMUNOLOGY, 1990, 2 (04) :353-360

[2] DEFECTIVE T-CELL RECEPTOR SIGNALING IN MICE LACKING THE THYMIC ISOFORM OF P59(FYN) [J].

APPLEBY, MW ;

GROSS, JA ;

COOKE, MP ;

LEVIN, SD ;

QIAN, X ;

PERLMUTTER, RM .

CELL, 1992, 70 (05) :751-763

[3] CD22-MEDIATED STIMULATION OF T-CELLS REGULATES T-CELL RECEPTOR CD3-INDUCED SIGNALING [J].

ARUFFO, A ;

KANNER, SB ;

SGROI, D ;

LEDBETTER, JA ;

STAMENKOVIC, I .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (21) :10242-10246

[4]

BELL GM, 1993, J IMMUNOL, V151, P3646

[5]

BORK P, 1993, PROTEIN SCI, V2, P1187

[6] HOMOPHILIC BINDING OF PTP-MU, A RECEPTOR-TYPE PROTEIN-TYROSINE-PHOSPHATASE, CAN MEDIATE CELL-CELL AGGREGATION [J].

BRADYKALNAY, SM ;

FLINT, AJ ;

TONKS, NK .

JOURNAL OF CELL BIOLOGY, 1993, 122 (04) :961-972

[7] CD45 CELL-SURFACE ANTIGENS ARE LINKED TO STIMULATION OF EARLY HUMAN MYELOID PROGENITOR CELLS BY INTERLEUKIN-3 (IL-3), GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR (GM-CSF), A GM-CSF IL-3 FUSION PROTEIN, AND MAST-CELL GROWTH-FACTOR (A C-KIT LIGAND) [J].

BROXMEYER, HE ;

LU, L ;

HANGOC, G ;

COOPER, S ;

HENDRIE, PC ;

LEDBETTER, JA ;

XIAO, M ;

WILLIAMS, DE ;

SHEN, FW .

JOURNAL OF EXPERIMENTAL MEDICINE, 1991, 174 (02) :447-458

[8] ZAP-70 - A 70 KD PROTEIN-TYROSINE KINASE THAT ASSOCIATES WITH THE TCR ZETA-CHAIN [J].

CHAN, AC ;

IWASHIMA, M ;

TURCK, CW ;

WEISS, A .

CELL, 1992, 71 (04) :649-662

[9] THE LEUKOCYTE COMMON ANTIGEN (CD45) - A PUTATIVE RECEPTOR-LINKED PROTEIN TYROSINE PHOSPHATASE [J].

CHARBONNEAU, H ;

TONKS, NK ;

WALSH, KA ;

FISCHER, EH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (19) :7182-7186

[10] CATALYTIC DOMAINS OF THE LAR AND CD45 PROTEIN TYROSINE PHOSPHATASES FROM ESCHERICHIA-COLI EXPRESSION SYSTEMS - PURIFICATION AND CHARACTERIZATION FOR SPECIFICITY AND MECHANISM [J].

CHO, HJ ;

RAMER, SE ;

ITOH, M ;

KITAS, E ;

BANNWARTH, W ;

BURN, P ;

SAITO, H ;

WALSH, CT .

BIOCHEMISTRY, 1992, 31 (01) :133-138

← 1 2 3 4 5 6 7 →