IMIDAZOLE BINDING-SITES IN RABBIT KIDNEY AND FOREBRAIN MEMBRANES

被引：37

作者：

HAMILTON, CA ^{[1
]}

YAKUBU, MA ^{[1
]}

JARDINE, E ^{[1
]}

REID, JL ^{[1
]}

机构：

[1] UNIV GLASGOW,STOBHILL GEN HOSP,DEPT MED & THERAPEUT,GLASGOW G21 3UW,SCOTLAND

来源：

JOURNAL OF AUTONOMIC PHARMACOLOGY | 1991年 / 11卷 / 04期

关键词：

D O I：

10.1111/j.1474-8673.1991.tb00325.x

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

1 The binding of [H-3]-clonidine, [H-3]-idazoxan and [H-3]-yohimbine to rabbit forebrain and kidney membranes was compared. 2 Yohimbine bound exclusively to adrenergic sites, idazoxan to non-adrenergic sites and clonidine to both non-adrenergic and adrenergic sites. 3 Differences were observed between the ligands not only in binding at adrenergic and non-adrenergic sites but also between the non-adrenergic binding of [H-3]-clonidine and [H-3]-idazoxan. 4 However, no tissue specific differences were found.

引用

页码：277 / 283

页数：7

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