ISOLATION, CHARACTERIZATION AND STRUCTURES OF PA-46101-A AND PA-46101-B

被引：44

作者：

MATSUMOTO, M

KAWAMURA, Y

YOSHIMURA, Y

TERUI, Y

NAKAI, H

YOSHIDA, T

SHOJI, J

机构：

[1] Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka 553, 5-12-4 Fukushima-ku, Sagisu

来源：

JOURNAL OF ANTIBIOTICS | 1990年 / 43卷 / 07期

关键词：

D O I：

10.7164/antibiotics.43.739

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

New antibiotics, PA-46101 A and B, were isolated from the culture broth of a Streptomycete. The molecular formulae of A and B were determined to be C52H70O18 and C61H86O22, respectively, by elemental analyses, NMR and mass spectrometry. Their structures were elucidated by X-ray crystallography and NMR spectroscopy. These antibiotics are active in vitro against anaerobic Gram-positive and Gram-negative bacteria and also against a limited number of aerobic Gram-positive bacteria. © 1990, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：739 / 747

页数：9

共 9 条

[1] RAPID DIFFERENTIATION BETWEEN NOCARDIA + STREPTOMYCES BY PAPER CHROMATOGRAPHY OF WHOLE-CELL HYDROLYSATES [J].