EFFECT OF THYROXINE ON BASAL AND INSULIN-STIMULATED GLUCOSE-UPTAKE BY FAST AND SLOW SKELETAL-MUSCLES OF RATS

被引：5

作者：

SHOJI, S

机构：

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-PHYSIOLOGY | 1991年 / 100卷 / 02期

关键词：

D O I：

10.1016/0300-9629(91)90479-V

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. The sc injection of 1-thyroxine (2 mg/kg bw/day) for 8 days produced a significant decrease of body weight gain in young male Wistar rats. 2. In these hyperthyroid rats there was a significant decrease in the wet weight of the extensor digitorum longus (EDL) and soleus (Sol) muscles as compared with those of control rats. 3. The basal glucose uptake by the EDL and Sol muscles was unchanged in hyperthyroid rats using the wet weight of muscle as a reference. 4. In hyperthyroid rats, the insulin-stimulated uptake of glucose by both the EDL and Sol muscles was significantly decreased. This inhibition was stronger in Sol and there was no insulin stimulation of glucose uptake by Sol.

引用

页码：343 / 345

页数：3

共 24 条

[1] INSULIN SECRETORY RESPONSE TO DIFFERENT SECRETAGOGUES IN HYPER-THYROID AND HYPOTHYROID MICE [J].