PREPARATION OF 5-(1-AMINOCYCLOHEXYL)-2(1H)-PYRIDINONES VIA THE RITTER REACTION

被引：4

作者：

FINK, DM

EFFLAND, RC

机构：

[1] Chemical Research Department Neuroscience Strategic Business Unit Hoechst-Roussel Pharmaceuticals Inc., Somerville, NJ 08876

来源：

SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 19期

关键词：

D O I：

10.1080/00397919408010597

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 5-(l-aminocyclohexyl)-2(1H)-pyrdinones was prepared in 16-32% yield. The key step is a Ritter reaction of the analogous alcohols. The results reported demonstrate the difference in reactivity between the closely related 2-alkoxy-pyridines and 2(1H)-pyridinones.

引用

页码：2793 / 2796

页数：4