ANALGESIC EFFECT OF TOPICAL DICLOFENAC VERSUS BETAMETHASONE AFTER POSTERIOR SEGMENT SURGERY

被引：11

作者：

LESNONI, G

COPPE, AM

MANNI, G

BILLI, B

STIRPE, M

机构：

[1] G. B. Bietti Foundation for Ophthalmology, Rome

[2] The Department of Ophthalmology, II University, “Tor Vergata”, Rome

来源：

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | 1995年 / 15卷 / 01期

关键词：

ANALGESIC EFFECT; BETAMETHASONE; DICLOFENAC; POSTERIOR SEGMENT SURGERY; MCGILL PAIN QUESTIONNAIRE; VISUAL ANALOGIC SCALE;

D O I：

10.1097/00006982-199515010-00007

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Background: In clinical use, topical diclofenac, a nonsteroidal antiinflammatory, was found to be remarkably effective as an analgesic. A trial was therefore conducted to quantify and compare this effect with that of other drugs commonly used after posterior segment surgery. Methods: A single-blind, randomized study of 37 patients undergoing posterior segment surgery was conducted. On the day of surgery and for 30 days thereafter, one group received topical diclofenac 0.1% and one group received topical betamethasone 0.1%. Pain intensity was assessed by two standard psychologic tests, the McGill Pain Questionnaire (MPQ) and Scott's Visual Analogic Scale (VAS). Results: The group receiving diclofenac had significantly lower pain scores on the MPQ at days 1 and 15 (P < 0.05 and P < 0.03, respectively). The VAS scores were also statistically lower for this group on day 15 (P < 0.03). Conclusion: Topical diclofenac 0.1% has greater analgesic action than topical betamethasone 0.1% without the side effects of steroids, and may be useful after posterior segment surgery.

引用

页码：34 / 36

页数：3

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