CIRCULATING ANTIBODIES AGAINST C-MYC ONCOGENE PRODUCT IN SERA OF COLORECTAL-CANCER PATIENTS

被引：67

作者：

BENMAHREZ, K

SOROKINE, I

THIERRY, D

KAWASUMI, T

ISHII, S

SALMON, R

KOHIYAMA, M

机构：

[1] CEA,IPSN,DPS,SHR,F-92260 FONTENAY ROSES,FRANCE

[2] RIKEN,TSUKUBA LIFE SCI CTR,TSUKUBA,IBARAKI 305,JAPAN

[3] INST CURIE,F-75231 PARIS 05,FRANCE

来源：

INTERNATIONAL JOURNAL OF CANCER | 1990年 / 46卷 / 01期

关键词：

D O I：

10.1002/ijc.2910460109

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We developed a Western blot assay using purified human c‐myc protein expressed in E. coli in order to look for circulating anti‐c‐myc antibodies in human sera. The presence of IgG antibodies against c‐myc was observed in 25 out of 44 sera from patients with colorectal cancer diagnosed and treated at the Hǒpital Curie in Paris, compared to the sera of 46 normal donors of which only 8 samples were positive (p = 0.001). Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company

引用

页码：35 / 38

页数：4

共 14 条

[1] THE PROGNOSTIC SIGNIFICANCE OF DIRECT EXTENSION OF CARCINOMA OF THE COLON AND RECTUM [J].