CARBON-DIOXIDE LASER-SURGERY OF ORAL LEUKOPLAKIA

被引:55
作者
ROODENBURG, JLN [1 ]
PANDERS, AK [1 ]
VERMEY, A [1 ]
机构
[1] STATE UNIV GRONINGEN HOSP,DEPT SURG ONCOL,9700 RB GRONINGEN,NETHERLANDS
来源
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS | 1991年 / 71卷 / 06期
关键词
D O I
10.1016/0030-4220(91)90271-D
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Oral leukoplakia is a precancerous lesion of the oral mucosa. The risk of malignant transformation depends on the clinical and histologic classification and the location of the lesion. For a nonhomogeneous leukoplakia, this risk is 23.4% to 38.0%. In the presence of epithelial dysplasia, the possibility of malignant transformation is 36.3% to 43.0%. Leukoplakia is limited to the epithelium, so a selective removal of this part of the mucosa seems to be the best preventive treatment. Carbon dioxide laser surgery accomplishes a superficial removal by evaporation. A total of 70 patients with 103 oral leukoplakias were treated with carbon dioxide laser evaporation. This resulted in an excellent wound healing with virtually no scarring. The patients were followed up during a period of up to 12 years (mean 5.3 years), showing a cure rate of 90%.
引用
收藏
页码:670 / 674
页数:5
相关论文
共 30 条
[1]  
ABSTEN GT, 1985, LASER MED INTRO GUID, P14
[2]   INVESTIGATION OF CARCINOGENIC EFFECTS OF INVITRO ARGON AND CO2-LASER EXPOSURE OF FIBROBLASTS [J].
APFELBERG, DB ;
MITTELMAN, H ;
CHADI, B ;
MASER, MR ;
LASH, H .
LASERS IN SURGERY AND MEDICINE, 1984, 4 (02) :173-179
[3]  
AXELL T, 1986, INT J ORAL MAXILLOF, V15, P790
[4]   OCCURRENCE OF EPITHELIAL DYSPLASIA IN ORAL LEUKOPLAKIA [J].
BANOCZY, J ;
CSIBA, A .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 1976, 42 (06) :766-774
[5]   FOLLOW-UP STUDIES IN ORAL LEUKOPLAKIA [J].
BANOCZY, J .
JOURNAL OF MAXILLOFACIAL SURGERY, 1977, 5 (01) :69-75
[6]  
Banoczy J, 1972, J Oral Pathol, V1, P265, DOI 10.1111/j.1600-0714.1972.tb01665.x
[7]  
BANOCZY J, 1972, CANCER, V29, P1230, DOI 10.1002/1097-0142(197205)29:5<1230::AID-CNCR2820290515>3.0.CO
[8]  
2-3
[9]   6 YEARS EXPERIENCE WITH CRYOSURGERY IN THE ORAL CAVITY [J].
BEKKE, JPH ;
BAART, JA .
INTERNATIONAL JOURNAL OF ORAL SURGERY, 1979, 8 (04) :251-270
[10]  
CHU FWK, 1988, LARYNGOSCOPE, V98, P125