CHANGES IN THE PLASMA AMINOGRAM OF PARENTERALLY FED INFANTS TREATED WITH DEXAMETHASONE FOR BRONCHOPULMONARY DYSPLASIA

被引：9

作者：

NG, PC

BROWNLEE, KG

KELLY, EJ

HENDERSON, MJ

SMITH, M

DEAR, PRF

机构：

[1] ST JAMES UNIV HOSP, DEPT PAEDIAT & CHILD HLTH, LEEDS LS9 7TF, W YORKSHIRE, ENGLAND

[2] ST JAMES UNIV HOSP, DEPT CHEM PATHOL, LEEDS LS9 7TF, W YORKSHIRE, ENGLAND

来源：

ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION | 1992年 / 67卷 / 10期

关键词：

D O I：

10.1136/adc.67.10_Spec_No.1193

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A substantial increase in the plasma concentration of most amino acids was observed in 59 Preterm infants with chronic lung disease soon after the initiation of dexamethasone therapy. The size of increase appeared to be dose related. This phenomenon is likely to be the result Of steroid induced protein catabolism. Interestingly, neither phenylalanine nor tyrosine concentrations were significantly increased.

引用

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页码：1193 / 1195

页数：3

相关论文

共 18 条

[1]

BJORKMAN O, 1987, LANCET, V1, P1311

[2] CATABOLIC EFFECT OF DEXAMETHASONE IN THE PRETERM BABY [J].

BROWNLEE, KG ;

NG, PC ;

HENDERSON, MJ ;

SMITH, M ;

GREEN, JH ;

DEAR, PRF .

ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 1992, 67 (01) :1-4

[3] PLASMA AMINO-ACID CONCENTRATIONS IN PARENTERALLY FED PRETERM INFANTS [J].

CLARK, D ;

HENDERSON, M ;

SMITH, M ;

DEAR, PRF .

ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 1989, 64 (07) :939-942

[4] A CONTROLLED TRIAL OF DEXAMETHASONE IN PRETERM INFANTS AT HIGH-RISK FOR BRONCHOPULMONARY DYSPLASIA [J].

CUMMINGS, JJ ;

DEUGENIO, DB ;

GROSS, SJ .

NEW ENGLAND JOURNAL OF MEDICINE, 1989, 320 (23) :1505-1510

[5] PHYSIOLOGICAL AND METABOLIC RESPONSE TO ISOLATED CLOSED-HEAD INJURY .2. EFFECTS OF STEROIDS ON METABOLISM - POTENTIATION OF PROTEIN WASTING AND ABNORMALITIES OF SUBSTRATE UTILIZATION [J].

DEUTSCHMAN, CS ;

KONSTANTINIDES, FN ;

RAUP, S ;

CERRA, FB .

JOURNAL OF NEUROSURGERY, 1987, 66 (03) :388-395

[6]

EVANS SJ, 1986, LANCET, V2, P1404

[7]

Fajans S S, 1967, Recent Prog Horm Res, V23, P617

[8] CATABOLIC EFFECT OF DEXAMETHASONE IN PATIENTS WITH MAJOR HEAD-INJURIES [J].

GREENBLATT, SH ;

LONG, CL ;

BLAKEMORE, WS ;

DENNIS, RS ;

RAYPORT, M ;

GEIGER, JW .

JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 1989, 13 (04) :372-376

[9] DEXAMETHASONE THERAPY FOR CHRONIC LUNG-DISEASE IN VENTILATOR-DEPENDENT AND OXYGEN-DEPENDENT INFANTS - A CONTROLLED TRIAL [J].

HARKAVY, KL ;

SCANLON, JW ;

CHOWDHRY, PK ;

GRYLACK, LJ .

JOURNAL OF PEDIATRICS, 1989, 115 (06) :979-983

[10] THE INFLUENCE OF GLUCOCORTICOID DOSE ON PROTEIN CATABOLISM AFTER RENAL-TRANSPLANTATION [J].

HOY, WE ;

SARGENT, JA ;

FREEMAN, RB ;

PABICO, RC ;

MCKENNA, BA ;

STERLING, WA .

AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 1986, 291 (04) :241-247