DELETION OF 3P25-]PTER IN A PRIMARY FOLLICULAR THYROID-CARCINOMA AND ITS METASTASIS

被引：34

作者：

ROQUE, L

CASTEDO, S

CLODE, A

SOARES, J

机构：

[1] HOSP SAO JOAO, MED FAC PORTO, DEPT MED GENET, P-4200 OPORTO, PORTUGAL

[2] UNIV PORTO, INST MOLEC PATHOL & IMMUNOL, IPATIMOP, OPORTO, PORTUGAL

[3] PORTUGUESE INST ONCOL, DEPT MORPHOL PATHOL, LISBON, PORTUGAL

来源：

GENES CHROMOSOMES & CANCER | 1993年 / 8卷 / 03期

关键词：

D O I：

10.1002/gcc.2870080311

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report the cytogenetic analysis of a follicular thyroid carcinoma and its bone metastasis. Both lesions had identical chromosomal abnormalities, with a der(3)t(2;3)(q13;p25) as the most likely primary clonal alteration. Our findings corroborate previous observations of frequent 3p deletions in thyroid follicular carcinomas and suggest that the minimal chromosomal region of loss in these tumors is 3p25 --> pter. (C) 1993 Wiley-Liss, Inc.

引用

页码：199 / 203

页数：5

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ROQUE, L ;

CASTEDO, S ;

CLODE, A ;

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GENES CHROMOSOMES & CANCER, 1992, 4 (04) :346-347

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