POLIOVIRUS TYPE-1 ENTERS THE HUMAN HOST THROUGH INTESTINAL M-CELLS

被引:167
作者
SICINSKI, P
ROWINSKI, J
WARCHOL, JB
JARZABEK, Z
GUT, W
SZCZYGIEL, B
BIELECKI, K
KOCH, G
机构
[1] MED ACAD WARSAW,DEPT GASTROENTEROL SURG,PL-02004 WARSAW,POLAND
[2] MED SCH POZNAN,DEPT HISTOL & EMBRYOL,POZNAN,POLAND
[3] NATL INST HYG,PL-00791 WARSAW,POLAND
[4] BIELANSKI HOSP,DEPT SURG,WARSAW,POLAND
[5] UNIV HAMBURG,DEPT MOLEC BIOL,W-2000 HAMBURG 13,GERMANY
关键词
D O I
10.1016/0016-5085(90)91290-M
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
It was demonstrated by electron microscopy that after in vitro incubation of human Peyer's patches with poliovirus type 1, either Sabin or Mahoney strain, poliovirus particles adhere specifically to and are endocytosed by intestinal epithelial M cells. These findings suggest that M cells in humans are the site of poliovirus penetration of the intestinal epithelial barrier. © 1990.
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页码:56 / 58
页数:3
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