DIASTEREOSELECTIVITY AND REGIOCONTROL IN INTRAMOLECULAR ALLYL CATION CYCLOADDITIONS - SELECTIVE FORMATION OF [3+2] OR [3+4] CYCLOADDUCTS

被引：36

作者：

GIGUERE, RJ ^{[1
]}

TASSELY, SM ^{[1
]}

ROSE, MI ^{[1
]}

KRISHNAMURTHY, VV ^{[1
]}

机构：

[1] VARIAN ASSOCIATES INC,DIV NUCL MAGNET RESONANCE INSTRUMENTS,FLORHAM PK,NJ 07932

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 32期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(00)97680-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Intramolecular Hoffmann-Noyori reactions of chiral, diastereomeric trienols 1a and 1b demonstrate site-selectivity control to form either [3+4] or [3+2] cycloadducts 2a and 2b, respectively. Furthermore, both reactions exhibit a high degree of diastereoselectivity. Cycloaddition precursors 1a,b are prepared from (-)-S-citronellol in 33% overall yield. © 1990.

引用

页码：4577 / 4580

页数：4

共 19 条

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