EPIDEMIC ASTHMA IN CARTAGENA, SPAIN, AND ITS ASSOCIATION WITH SOYBEAN SENSITIVITY

被引:33
作者
NAVARRO, C
MARQUEZ, M
HERNANDO, L
GALVAN, F
ZAPATERO, L
CARAVACA, F
机构
[1] Epidemiology Department, Murcia
[2] Chest Diseases Dispensary, Murcia Health Council, Murcia
[3] Allergy Department, Hospital Santa Maria del Rosell, Cartagena
关键词
ASTHMA; DISEASE OUTBREAKS; CASE-CONTROL STUDIES; SOYBEANS; SKIN TESTS; IGE ANTIBODIES; ALLERGENS;
D O I
10.1097/00001648-199301000-00014
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
We conducted a matched case-control study to assess the association between epidemic asthma and soybean sensitivity in Cartagena, Spain. In skin tests, 81% of the cases and no control subjects were positive to the commercial soybean allergen; 87% of the cases and 12% of the controls were positive to the prepared soybean allergen; and 69% of the cases and 6% of the controls showed high levels of specific immunoglobulin E antibodies (odds ratio = 10; 95% confidence interval = 1.4-433). The association remained strong after adjustment for total immunoglobulin E and for 28 other allergens. The results indicate that soybean sensitivity may be causing asthma epidemics in Cartagena.
引用
收藏
页码:76 / 79
页数:4
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