CRYSTAL-STRUCTURE AND ISOMERISM OF A TUMOR TARGETING RADIOPHARMACEUTICAL - [REO(DMSA)2]- (H2DMSA = MESO-2,3-DIMERCAPTOSUCCINIC ACID)

被引：39

作者：

SINGH, J

POWELL, AK

CLARKE, SEM

BLOWER, PJ

机构：

[1] KENT & CANTERBURY HOSP,DEPT NUCL MED,CANTERBURY CT1 3NG,ENGLAND

[2] UNIV KENT,BIOL LAB,CANTERBURY CT2 7NJ,ENGLAND

[3] UNIV E ANGLIA,DEPT CHEM,NORWICH NR4 7TJ,NORFOLK,ENGLAND

[4] GUYS HOSP,DEPT NUCL MED,LONDON SE1,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 16期

关键词：

D O I：

10.1039/c39910001115

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A crystal structure determination shows that one isomer of the complex anion [ReO(dmsa)2]- (H2dmsa = meso-2,3-dimercaptosuccinic acid), a compound which in radiopharmaceutical form has been shown to localise in certain human tumours, has a square-pyramidal structure with all carboxylic acid groups uncoordinated and oriented endo relative to the oxo ligand.

引用

页码：1115 / 1117

页数：3

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