ENZYMATIC DEGRADATION OF PEPSTATIN A TO A NEW TETRAPEPTIDE

被引：5

作者：

TONE, H

SHIBAMOTO, N

MATSUSHITA, Y

INUI, T

TAKAMATSU, A

AOYAGI, T

TAKEUCHI, T

UMEZAWA, H

机构：

[1] SANRAKU OCEAN CO LTD,CENT RES LABS,9-1 JOHNAN 4 CHO,FUJISAWA,JAPAN

[2] INST MICROBIAL CHEM,3-14-23 KAMIOSAKI,SHINAGAWA,TOKYO,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1975年 / 28卷 / 12期

关键词：

D O I：

10.7164/antibiotics.28.1009

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：1009 / 1011

页数：3

共 12 条

[1] NEW PEPSTATINS, PEPSTATINS BU, PR AND AC PRODUCED BY STREPTOMYCES [J].

AOYAGI, T ;

YAGISAWA, Y ;

KUMAGAI, M ;

HAMADA, M ;

MORISHIMA, H ;

TAKEUCHI, T ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1973, 26 (09) :539-541

[2] EFFECT OF PEPSTATIN ON ACID PROTEASES [J].

AOYAGI, T ;

KUNIMOTO, S ;

MORISHIMA, H ;

TAKEUCHI, T ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1971, 24 (10) :687-+

[3] BIOLOGICAL-ACTIVITY OF PEPSTATINS, PEPSTANONE A AND PARTIAL PEPTIDES ON PEPSIN, CATHEPSIN D AND RENIN [J].

AOYAGI, T ;

MORISHIMA, H ;

NISHIZAWA, R ;

KUNIMOTO, S ;

TAKEUCHI, T ;

UMEZAWA, H ;

IKEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1972, 25 (12) :689-694

[4] INHIBITION OF RENIN-ANGIOTENSINOGEN REACTION BY PEPSTATIN [J].

GROSS, F ;

LAZAR, J ;

ORTH, H .

SCIENCE, 1972, 175 (4022) :656-&

[5] EFFECT OF PROTEASE INHIBITORS OF ACTINOMYCETES ON LYSOSOMAL PEPTIDE-HYDROLASES FROM SWINE LIVER [J].

IKEZAWA, H ;

AOYAGI, T ;

TAKEUCHI, T ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1971, 24 (07) :488-&

[6] MECHANISM OF INHIBITION OF PEPSIN BY PEPSTATIN [J].

KUNIMOTO, S ;

AOYAGI, T ;

TAKEUCHI, T ;

UMEZAWA, H ;

MORISHIMA, H .

JOURNAL OF ANTIBIOTICS, 1972, 25 (04) :251-+

[7] NEW PEPSTATINS, PEPSTATINS-B AND C, AND PEPSTANONE-A, PRODUCED BY STREPTOMYCES [J].

MIYANO, T ;

UMEZAWA, H ;

TAKITA, T ;

TOMIYASU, M ;

TOMISAKA, S ;

IIZUKA, H ;

AOYAGI, T .

JOURNAL OF ANTIBIOTICS, 1972, 25 (08) :489-&

[8] STRUCTURE OF PEPSTATIN [J].

MORISHIMA, H ;

TAKITA, T ;

AOYAGI, T ;

TAKEUCHI, T ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1970, 23 (05) :263-+

[9] CHEMICAL SYNTHESIS OF PEPSTATIN-A [J].

MORISHIMA, H ;

TAKITA, T ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1972, 25 (09) :551-+

[10] PURIFICATION AND PROPERTIES OF PEPSTATIN HYDROLASE FROM BACILLUS-SPHAERICUS [J].

TONE, H ;

MATSUSHITA, Y ;

YAGI, Y ;

TAKAMATSU, A ;

AOYAGI, T ;

TAKEUCHI, T ;

UMEZAWA, H .

JOURNAL OF ANTIBIOTICS, 1975, 28 (12) :1012-1015

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