IMPROVED SYNTHESIS OF OLIGODEOXYNUCLEOTIDES ON CONTROLLED PORE GLASS USING PHOSPHOTRIESTER CHEMISTRY AND A FLOW SYSTEM

被引：67

作者：

SPROAT, BS ^{[1
]}

BANNWARTH, W ^{[1
]}

机构：

[1] HOFFMANN LAROCHE & CO AG,ZENT FORSCH EINHEITEN,CH-4002 BASEL,SWITZERLAND

来源：

TETRAHEDRON LETTERS | 1983年 / 24卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(00)94197-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：5771 / 5774

页数：4

共 9 条

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[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (03) : 661 - 663
[2] 9-PHENYLXANTHEN-9-YL PROTECTING GROUP
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[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1978, (15) : 639 - 640
[3] NEW EFFECTIVE METHOD FOR THE SYNTHESIS OF OLIGONUCLEOTIDES VIA PHOSPHOTRIESTER INTERMEDIATES
EFIMOV, VA
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CHAKHMAKHCHEVA, OG
[J]. NUCLEIC ACIDS RESEARCH, 1982, 10 (21) : 6675 - 6694
[4] STUDIES ON POLYNUCLEOTIDES .146. HIGH-PRESSURE LIQUID-CHROMATOGRAPHY IN POLYNUCLEOTIDE SYNTHESIS
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[J]. BIOCHEMISTRY, 1978, 17 (07) : 1257 - 1267
[5] RAPID SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDES .7. SOLID-PHASE SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDES BY A CONTINUOUS-FLOW PHOSPHOTRIESTER METHOD ON A KIESELGUHR-POLYAMIDE SUPPORT
GAIT, MJ
MATTHES, HWD
SINGH, M
SPROAT, BS
TITMAS, RC
[J]. NUCLEIC ACIDS RESEARCH, 1982, 10 (20) : 6243 - 6254
[6] IMPROVEMENTS IN THE PHOSPHOTRIESTER SYNTHESIS OF DEOXYRIBOOLIGONUCLEOTIDES - THE USE OF HINDERED PRIMARY AMINES AND A NEW ISOLATION PROCEDURE
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[J]. TETRAHEDRON LETTERS, 1982, 23 (49) : 5119 - 5122
[7] SILICA-GEL - AN IMPROVED SUPPORT FOR THE SOLID-PHASE PHOSPHOTRIESTER SYNTHESIS OF OLIGONUCLEOTIDES
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BALLAND, A
WINTZERITH, M
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STAUB, A
LECOCQ, JP
[J]. NUCLEIC ACIDS RESEARCH, 1982, 10 (22) : 7439 - 7448
[8] KOSTER H, 1983, TETRAHEDRON LETT, V24, P747, DOI 10.1016/S0040-4039(00)81515-4
[9] WAKABAYASHI T, 1982, CHEM PHARM BULL, V30, P3951

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