学术探索
学术期刊
新闻热点
数据分析
智能评审

THE ROLE OF CALCITONIN GENE-RELATED PEPTIDE IN GASTRIC-MUCOSAL PROTECTION IN THE RAT

被引：21
作者：
FORSTER, ER
DOCKRAY, GJ
机构：
来源：
EXPERIMENTAL PHYSIOLOGY | 1991年 / 76卷 / 04期
关键词：
D O I：
10.1113/expphysiol.1991.sp003532
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
The presence of circulating antibodies to calcitonin gene-related peptide (CGRP) enhanced the damaging effect of ethanol on the rat gastric mucosa. Taken together with previous experimental and morphological data the results suggest that CGRP released from the peripheral terminals of visceral afferent fibres plays a role in mediating gastric mucosal defence mechanisms.
引用
收藏
页码：623 / 626
页数：4
相关论文
共 5 条
[1]   THE BROWN,G.L. LECTURE - REGULATORY PEPTIDES AND THE NEUROENDOCRINOLOGY OF GUT BRAIN RELATIONS [J].
DOCKRAY, GJ .
QUARTERLY JOURNAL OF EXPERIMENTAL PHYSIOLOGY AND COGNATE MEDICAL SCIENCES, 1988, 73 (05) :703-727
[2]   AFFERENT NERVE-MEDIATED PROTECTION AGAINST DEEP MUCOSAL DAMAGE IN THE RAT STOMACH [J].
HOLZER, P ;
PABST, MA ;
LIPPE, IT ;
PESKAR, BM ;
PESKAR, BA ;
LIVINGSTON, EH ;
GUTH, PH .
GASTROENTEROLOGY, 1990, 98 (04) :838-848
[3]   GASTRIC-MUCOSAL PROTECTION AGAINST ULCEROGENIC FACTORS IN THE RAT MEDIATED BY CAPSAICIN-SENSITIVE AFFERENT NEURONS [J].
HOLZER, P ;
SAMETZ, W .
GASTROENTEROLOGY, 1986, 91 (04) :975-981
[4]   IMMUNIZATION WITH CALCITONIN GENE-RELATED PEPTIDE REDUCES THE INFLAMMATORY RESPONSE TO ADJUVANT ARTHRITIS IN THE RAT [J].
LOUIS, SM ;
JOHNSTONE, D ;
MILLEST, AJ ;
RUSSELL, NJW ;
DOCKRAY, GJ .
NEUROSCIENCE, 1990, 39 (03) :727-731
[5]   INTERACTIONS BETWEEN THE VASCULAR PEPTIDE ENDOTHELIN-1 AND SENSORY NEUROPEPTIDES IN GASTRIC-MUCOSAL INJURY [J].
WHITTLE, BJR ;
LOPEZBELMONTE, J .
BRITISH JOURNAL OF PHARMACOLOGY, 1991, 102 (04) :950-954
1