FACTORS ASSOCIATED WITH FAILURE OF PASSIVE TRANSFER OF COLOSTRAL ANTIBODIES IN STANDARD-BRED FOALS

被引:47
作者
CLABOUGH, DL
LEVINE, JF
GRANT, GL
CONBOY, HS
机构
[1] College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina
[2] Lexington, Kentucky
关键词
D O I
10.1111/j.1939-1676.1991.tb03147.x
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The records of 361 Standardbred mares and their 1986 or 1987 foals were evaluated to identify factors associated with failure of passive transfer (FPT) of colostral antibodies in equine neonates. Sixty-five foals (18%) were classified as FPT based on a serum immunoglobulin concentration of < 400 mg/dl at 24 to 36 hours of age, determined by the glutaraldehyde coagulation test. The potential association of mare-and foal-related factors with FPT were assessed by reviewing a series of multiple logistic regression models. The season in which the mare foaled and foal exam score a subjective assessment of foal vigor, maturity, and general health, were the primary factors associated with the development of FPT. Foals with FPT were more likely (odds ratio = 3.50; 95% confidence interval = 1.81-6.68) than normal foals to require medical therapy during the first 3 months after parturition.
引用
收藏
页码:335 / 340
页数:6
相关论文
共 29 条
[1]  
Mason JH, Dalling T., Gordon WS., Transmission of maternal immunity, The Journal of Pathology and Bacteriology, 33, pp. 783-793, (1930)
[2]  
Jeffcott LB., Duration of permeability of the intestine to macromolecules in the newly born foal, Vet Rec, 88, pp. 340-341, (1971)
[3]  
Jeffcott LB., The transfer of passive immunity to the foal and its relation to immune status after birth, J Reprod Fertil, 23, pp. 727-733, (1975)
[4]  
Rejnek J., Prokesova L., Sterzl J., Et al., The presence of IgG and IgM in full term horse umbilical cord sera, Immunochemistry, 10, pp. 397-399, (1973)
[5]  
McGuire TC, Poppie MJ, Banks KL., Hypogammaglobulinemia predisposing to infection in foals, J Am Vet Med Assoc, 166, pp. 71-75, (1975)
[6]  
McGuire TC, Crawford TB, Halliwell AI, Et al., Failure of colostral immunoglobulin transfer as an explanation for most infections and deaths of neonatal foals, J Am Vet Med Assoc, 170, pp. 1302-1304, (1977)
[7]  
Brewer BD, Koterba AM., The diagnosis and treatment of equine neonatal septicemia, in Proceedings, Ann Meet Am Assoc Equine Pract, 31, pp. 127-135, (1985)
[8]  
Koterba AM, Brewer BD, Tarplee FA., Clinical and clinicopathological characteristics of the septicaemic neonatal foal: review of 38 cases, Equine Vet J, 16, pp. 376-383, (1984)
[9]  
Morris DD, Meirs DA, Merryman GS., Passive transfer failure in horses: incidence and causative factors on a breeding farm, Am J Vet Res, 46, pp. 2294-2299, (1985)
[10]  
Beetson SA, Hubert BJ, Mills JN., The use of the glutaraldehyde coagulation test for the detection of hypogammaglobulinaemia in neonatal foals, Aust Vet J, 62, pp. 279-281, (1986)