ISOZYME-SPECIFIC ENZYME-INHIBITORS .10. ADENOSINE 5'-TRIPHOSPHATE DERIVATIVES AS SUBSTRATES OR INHIBITORS OF METHIONINE ADENOSYLTRANSFERASES OF RAT NORMAL AND HEPATOMA TISSUES

被引：14

作者：

KAPPLER, F ^{[1
]}

HAI, TT ^{[1
]}

HAMPTON, A ^{[1
]}

机构：

[1] FOX CHASE CANC CTR,INST CANC RES,PHILADELPHIA,PA 19111

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 03期

关键词：

D O I：

10.1021/jm00153a003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：318 / 322

页数：5

共 29 条

[1] PARTIAL-PURIFICATION AND CHARACTERIZATION OF LENTICULAR S-ADENOSYLMETHIONINE SYNTHETASE [J].

AHMAD, SS ;

AHMAD, SI ;

RAHMAN, MA .

OPHTHALMIC RESEARCH, 1982, 14 (01) :9-21

[2]

BABKINA GT, 1973, IZV SIBIRSK OTD AKAD, V14, P74

[3] HYPER-METHIONINEMIA ASSOCIATED WITH METHIONINE ADENOSYLTRANSFERASE DEFICIENCY - CLINICAL, MORPHOLOGIC, AND BIOCHEMICAL OBSERVATIONS ON FOUR PATIENTS [J].

GAULL, GE ;

TALLAN, HH ;

LONSDALE, D ;

PRZYREMBEL, H ;

SCHAFFNER, F ;

VONBASSEWITZ, DB .

JOURNAL OF PEDIATRICS, 1981, 98 (05) :734-741

[4] CYCLIZATION OF PHOSPHATE SIDE-CHAIN OF ADENOSINE-TRIPHOSPHATE - FORMATION OF MONOADENOSINE 5'-TRIMETAPHOSPHATE [J].

GLONEK, T ;

KLEPS, RA ;

MYERS, TC .

SCIENCE, 1974, 185 (4148) :352-355

[5]

GOUT JP, 1977, ARCH FR PEDIATR, V34, P416

[6] SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME-INHIBITORS .7. SELECTIVE EFFECTS IN INHIBITIONS OF RAT ADENYLATE KINASE ISOZYMES BY ADENOSINE 5'-PHOSPHATE DERIVATIVES [J].

HAI, TT ;

PICKER, D ;

ABO, M ;

HAMPTON, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (07) :806-812

[7] DESIGN OF SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME-INHIBITORS .2. DIFFERENCES BETWEEN A BACTERIAL AND A MAMMALIAN THYMIDINE KINASE IN THE EFFECT OF THYMIDINE SUBSTITUENTS ON AFFINITY FOR THE THYMIDINE SITE [J].

HAMPTON, A ;

KAPPLER, F ;

CHAWLA, RR .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (12) :1524-1528

[8] USE OF ADENINE-NUCLEOTIDE DERIVATIVES TO ASSESS POTENTIAL OF EXO-ACTIVE-SITE-DIRECTED REAGENTS AS SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME INACTIVATORS .2. ISOZYME-SPECIFIC INACTIVATION OF A MAMMALIAN ENZYME AND ITS SIGNIFICANCE IN POSSIBLE DESIGN OF FETAL ISOENZYME TARGETED ANTI-NEOPLASTIC AGENTS [J].

HAMPTON, A ;

KAPPLER, F ;

MAEDA, M ;

PATEL, AD .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (11) :1137-1140

[9] SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME-INHIBITORS .4. DESIGN OF A 2-SITE INHIBITOR OF ADENYLATE KINASE WITH ISOENZYME SELECTIVITY [J].

HAMPTON, A ;

KAPPLER, F ;

PICKER, D .

JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (06) :638-644

[10] DESIGN OF SPECIES-SPECIFIC OR ISOZYME-SPECIFIC ENZYME-INHIBITORS .3. SPECIES AND ISOZYMIC DIFFERENCES BETWEEN MAMMALIAN AND BACTERIAL ADENYLATE KINASES IN SUBSTITUENT TOLERANCE IN AN ENZYME-SUBSTRATE COMPLEX [J].

HAMPTON, A ;

PICKER, D .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (12) :1529-1532

← 1 2 3 →