MUPIROCIN - A NEW TOPICAL ANTIBIOTIC

被引:13
作者
LEYDEN, JJ
机构
[1] Philadelphia, Pennsylvania
关键词
D O I
10.1016/0190-9622(90)70117-Z
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
One hundred fifty-three strains of Staphylococcus aureus recovered from infected eczema frequently demonstrated resistance to multiple antibiotics. PenicUlin and ampicillin resistance was extremely frequent (88%), methicillin resistance was found in nearly 14% of strains, and erythromycin and tetracycline resistance was present in 16%. S. aureus strains were uniformly sensitive to vancomycin, mupirocin, and cephalosporins. Experimental infections in human volunteers showed topical therapy with 2% mupirocin was more effective than oral erythromycin in suppression of both S. aureus and Streptococcus pyogenes. © 1990, American Academy of Dermatology, Inc.. All rights reserved.
引用
收藏
页码:879 / 883
页数:5
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