ARCHAEBACTERIAL LIPID MODELS - HIGHLY THERMOSTABLE MEMBRANES FROM 1,1'-(1,32-DOTRIACONTAMETHYLENE)-BIS(2-PHYTANYL-SN-GLYCERO-3-PHOSPHOCHOLINE)

被引：90

作者：

YAMAUCHI, K ^{[1
]}

SAKAMOTO, Y ^{[1
]}

MORIYA, A ^{[1
]}

YAMADA, K ^{[1
]}

HOSOKAWA, T ^{[1
]}

HIGUCHI, T ^{[1
]}

KINOSHITA, M ^{[1
]}

机构：

[1] OSAKA CITY UNIV,DEPT CHEM,SUMIYOSHI KU,OSAKA 558,JAPAN

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1990年 / 112卷 / 08期

关键词：

D O I：

10.1021/ja00164a047

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1,1'-(1,32-Dotriacontamethylene)bis[2-(3'RS, 7'R, 11'R)-phytanyl-sn-glycero-3-phosphocholine] was synthesized as a model of archaebacterial thermophile lipids. Upon sonication, the bipolar lipid furnished stable unilamellar vesicles of 400-1000-Å diameter and about 50-Å thickness. The liposomes, despite the low gel-to-liquid crystalline phase transition temperature (8 °C), could retain 5(6)-carboxyfluorescein and phospholipase A2-fluorescein isothiocyanate conjugates in the interior remarkably well even at 80 °C. © 1990, American Chemical Society. All rights reserved.

引用

页码：3188 / 3191

页数：4

共 24 条

[1]

BARTLETT GR, 1959, J BIOL CHEM, V234, P466

[2] SULFOLOBUS - NEW GENUS OF SULFUR-OXIDIZING BACTERIA LIVING AT LOW PH AND HIGH-TEMPERATURE [J].

BROCK, TD ;

BROCK, KM ;

BELLY, RT ;

WEISS, RL .

ARCHIV FUR MIKROBIOLOGIE, 1972, 84 (01) :54-&

[3]

DENNIS EA, 1983, ENZYMES, V16, pCH9

[4] STRUCTURE, BIOSYNTHESIS, AND PHYSICOCHEMICAL PROPERTIES OF ARCHAEBACTERIAL LIPIDS [J].

DEROSA, M ;

GAMBACORTA, A ;

GLIOZZI, A .

MICROBIOLOGICAL REVIEWS, 1986, 50 (01) :70-80

[5]

DEROSA M, 1985, J MOL BIOL, V182, P131

[6]

DITTMER JC, 1964, J LIPID RES, V5, P126

[7] ELECTROPHORETIC ANALYSIS OF MAJOR POLYPEPTIDES OF HUMAN ERYTHROCYTE MEMBRANE [J].

FAIRBANKS, G ;

STECK, TL ;

WALLACH, DFH .

BIOCHEMISTRY, 1971, 10 (13) :2606-+

[8]

FRANKS NP, 1981, LIPOSOMES PHYSICAL S, pCH8

[9] BOLAAMPHIPHILES FORM ULTRATHIN, POROUS, AND UNSYMMETRIC MONOLAYER LIPID-MEMBRANES [J].

FUHRHOP, JH ;

FRITSCH, D .

ACCOUNTS OF CHEMICAL RESEARCH, 1986, 19 (05) :130-137

[10] HARD ACID AND SOFT NUCLEOPHILE SYSTEM - NEW EFFICIENT METHOD FOR REMOVAL OF BENZYL PROTECTING GROUP [J].

FUJI, K ;

ICHIKAWA, K ;

NODE, M ;

FUJITA, E .

JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (10) :1661-1664

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