CARDIOVASCULAR PROTECTION BY ESTROGEN - A CALCIUM-ANTAGONIST EFFECT

被引：261

作者：

COLLINS, P ^{[1
]}

ROSANO, GMC ^{[1
]}

JIANG, CW ^{[1
]}

LINDSAY, D ^{[1
]}

SARREL, PM ^{[1
]}

POOLEWILSON, PA ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,NEW HAVEN,CT 06520

来源：

LANCET | 1993年 / 341卷 / 8855期

关键词：

D O I：

10.1016/0140-6736(93)91158-I

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

During their Premenopausal years, women have a lower risk than men of getting cardiovascular disease. This protection continues after the menopause if women receive oestrogen replacement. Based on new experimental evidence we propose that some of the cardiovascular benefits of oestrogen replacement therapy may be due to a long-term calcium antagonist effect of oestrogen.

引用

页码：1264 / 1265

页数：2

共 21 条

[1]

ADAMS MR, 1990, OVARIAN SECRETIONS C, P151

[2]

BRASS LM, 1990, J CARDIOVASC TECHNOL, V9, P68

[3]

CHELSKY R, 1990, CIRCULATION, V82, P111

[4]

HEMOGLOBIN INHIBITS ENDOTHELIUM-DEPENDENT RELAXATION TO ACETYLCHOLINE IN HUMAN CORONARY-ARTERIES INVIVO [J].