DETECTION OF WEST NILE AND JAPANESE ENCEPHALITIS VIRAL GENOME SEQUENCES IN CEREBROSPINAL-FLUID FROM ACUTE ENCEPHALITIS CASES IN KARACHI, PAKISTAN

被引：91

作者：

IGARASHI, A

TANAKA, M

MORITA, K

TAKASU, T

AHMED, A

AKRAM, DS

WAQAR, MA

机构：

[1] NIHON UNIV,SCH MED,DEPT NEUROL,BUNKYO KU,TOKYO 101,JAPAN

[2] CIVIL HOSP,DOW MED COLL,DEPT NEUROL,KARACHI,PAKISTAN

[3] CIVIL HOSP,DOW MED COLL,DEPT PEDIAT,KARACHI,PAKISTAN

[4] AGA KHAN UNIV,FAC HUMAN SCI,DEPT BIOCHEM,KARACHI,PAKISTAN

来源：

MICROBIOLOGY AND IMMUNOLOGY | 1994年 / 38卷 / 10期

关键词：

WEST NILE VIRUS; JAPANESE ENCEPHALITIS VIRUS; PCR; CSF;

D O I：

10.1111/j.1348-0421.1994.tb01866.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Reverse transcriptase-polymerase chain reaction (RT-PCR) on 24 cerebrospinal fluid (CSF) specimens collected between February and August 1992 detected genome sequence of West Nile (WN) virus in 8 specimens and Japanese encephalitis (JE) virus in a single specimen. The results, combined with the data by IgM-ELISA on CSF indicated that a significant proportion of acute encephalitis cases in Karachi, Pakistan, were caused by WN virus infection, while JE virus caused a small fraction.

引用

页码：827 / 830

页数：4

共 27 条

[1]

BARNETT HC, 1966, JPN MED SCI BIOL, V20, P19

[2] ANTIBODY-CAPTURE ELISA FOR DETECTION OF IMMUNOGLOBULIN-M ANTIBODIES IN SERA FROM JAPANESE ENCEPHALITIS AND DENGUE HEMORRHAGIC-FEVER PATIENTS [J].