ELEVATED PLASMA-IMMUNOREACTIVE BETA-ENDORPHIN IN ANOREXIA-NERVOSA

被引：15

作者：

TEPPER, R

WEIZMAN, A

APTER, A

TYANO, S

BEYTH, Y

机构：

[1] BEILINSON MED CTR, GEHA PSYCHIAT HOSP, POB 102, IL-49100 PETAH TIQWA, ISRAEL

[2] SAPIR MED CTR, DEPT OBSTET & GYNECOL, KEFAR SAVA, ISRAEL

[3] TEL AVIV UNIV, SACKLER SCH MED, IL-69978 TEL AVIV, ISRAEL

来源：

CLINICAL NEUROPHARMACOLOGY | 1992年 / 15卷 / 05期

关键词：

ANOREXIA NERVOSA; BETA-ENDORPHIN; HYPOGONADISM; STARVATION; STRESS;

D O I：

10.1097/00002826-199210000-00006

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Basal morning plasma levels of immunoreactive-beta-endorphin (ir-beta-EP), and 17-beta estradiol (E2) were assessed in 25 adolescents with anorexia nervosa (AN) in comparison to 24 healthy controls. All subjects were drug free for at least 6 weeks. The mean plasma level of ir-beta-EP was significantly higher (84%) in the AN patients when compared with the control subjects. The elevated plasma ir-beta-EP may be relevant to the suppression of appetite, tolerance of fasting, and to the hypothalamic hypogonadism in AN.

引用

页码：387 / 391

页数：5

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