RELEVANCE OF CHLORINE-SUBSTITUENT FOR THE ANTIFUNGAL ACTIVITY OF SYRINGOMYCIN AND SYRINGOTOXIN, METABOLITES OF THE PHYTOPATHOGENIC BACTERIUM PSEUDOMONAS-SYRINGAE PV SYRINGAE

被引：39

作者：

GRGURINA, I

BARCA, A

CERVIGNI, S

GALLO, M

SCALONI, A

PUCCI, P

机构：

[1] UNIV FEDERICO II,DIPARTIMENTO BIOCHIM & BIOTECNOL MED,I-80134 NAPLES,ITALY

[2] UNIV FEDERICO II,DIPARTIMENTO CHIM ORGAN & BIOL,I-80134 NAPLES,ITALY

来源：

EXPERIENTIA | 1994年 / 50卷 / 02期

关键词：

PSEUDOMONAS SYRINGAE PV SYRINGAE; SYRINGOMYCIN; SYRINGOTOXIN; STRUCTURAL ANALOGS; ANTIBIOTIC ACTIVITY;

D O I：

10.1007/BF01984950

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Structural analogues of syringomycin and syringotoxin were produced by fermentation, characterized by FAB-MS and amino acid analysis and compared to the parent compounds in the antibiosis test against Rhodotorula pilimanae. The C-terminal residue was shown to be important for the activity.

引用

页码：130 / 133

页数：4

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