THE PHASE-DIAGRAM OF DIMYRISTOYL PHOSPHATIDYLCHOLINE AND CHAIN-PERDEUTERATED DISTEAROYL PHOSPHATIDYLCHOLINE - A DEUTERIUM NMR SPECTRAL DIFFERENCE STUDY

被引：27

作者：

MORROW, MR

SRINIVASAN, R

GRANDAL, N

机构：

[1] Department of Physics, Memorial University of Newfoundland, St. John's

来源：

CHEMISTRY AND PHYSICS OF LIPIDS | 1991年 / 58卷 / 1-2期

基金：

加拿大自然科学与工程研究理事会;

关键词：

BINARY MIXTURE; PHASE DIAGRAM; NMR-H-2; GEL PHASE MISCIBILITY;

D O I：

10.1016/0009-3084(91)90112-O

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The phase diagram for mixtures of the lipids dimyristoylphosphatidylcholine (DMPC) and chain perdeuterated distearoylphosphatidylcholine (DSPC-d70) is determined using H-2-NMR difference spectroscopy. It is found that the temperature of the solidus line increases monotonically with DSPC-d70 concentration and thus that there is no evidence for peritectic behavior in this mixture. This phase diagram is compared to others that have been determined for DMPC/DSPC mixtures and for mixtures of perdeuterated DMPC (DMPC-d54) with DSPC some of which do display peritectic behavior. The possibility that different isotopic compositions give rise to qualitatively different phase diagrams for this system is discussed.

引用

页码：63 / 72

页数：10

共 28 条

[1]

[Anonymous], 1969, DATA REDUCTION ERROR

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