INVIVO MEASUREMENT OF THE VOLUME OF DISTRIBUTION OF WATER IN CEREBRAL GRAY-MATTER - EFFECTS ON THE CALCULATION OF REGIONAL CEREBRAL BLOOD-FLOW

被引：17

作者：

LAMMERTSMA, AA

MARTIN, AJ

FRISTON, KJ

JONES, T

机构：

[1] MRC Cyclotron Unit, Hammersmith Hospital, London

[2] MRC Cyclotron Unit, Hammersmith Hospital, London W12 0HS, Ducane Road

来源：

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM | 1992年 / 12卷 / 02期

关键词：

VOLUME OF DISTRIBUTION OF WATER; CEREBRAL BLOOD FLOW; O-15 LABELED CO-2; GRAY MATTER; POSITRON EMISSION TOMOGRAPHY;

D O I：

10.1038/jcbfm.1992.39

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The present study was undertaken to determine the apparent value for the volume of distribution of water to be used in the dynamic/integral technique for generating functional CBF images. A value of 0.86 resulted in only a minor loss of accuracy compared to the more accurate (but time-consuming) dynamic only analysis, which incorporated the regionally fitted estimates of the volume of distribution of water. In contrast to the traditionally used in vitro value of 0.95, the value of 0.86 allows for the inclusion of a significant part of the washout phase in the integral analysis, thereby producing statistically improved CBF images.

引用

页码：291 / 295

页数：5

共 9 条

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