(-)-DIHYDRO-APOVINCAMINIC ACID ETHYL-ESTER, PREPARATION AND USE AS A CHIRAL MODIFIER IN ENANTIOSELECTIVE HETEROGENEOUS CATALYTIC HYDROGENATIONS

被引：54

作者：

TUNGLER, A

MATHE, T

TARNAI, T

FODOR, K

TOTH, G

KAJTAR, J

KOLOSSVARY, I

HERENYI, B

SHELDON, RA

机构：

[1] HUNGARIAN ACAD SCI, ORGAN CHEM TECHNOL RES GRP, BUDAPEST, HUNGARY

[2] TECH UNIV BUDAPEST, HAS, DEPT GEN & ANALYT CHEM, TECH ANALYT RES GRP, BUDAPEST, HUNGARY

[3] EOTVOS LORAND UNIV, DEPT ORGAN CHEM, BUDAPEST, HUNGARY

[4] TECH UNIV BUDAPEST, DEPT CHEM INFORMAT TECHNOL, BUDAPEST, HUNGARY

[5] GEDEON RICHTER CO, BUDAPEST, HUNGARY

[6] DELFT UNIV TECHNOL, ORGAN CHEM & CATALYSIS LAB, DELFT, NETHERLANDS

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 09期

关键词：

D O I：

10.1016/0957-4166(95)00317-I

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The preparation, characterisation and use of (-)-dihydro-apovincaminic acid ethyl ester as a chiral modifier in heterogeneous catalytic asymmetric hydrogenations is reported. The epimeric compositions were determined using NMR and HPLC methods and circular dichroism spectroscopy was used to detect the interaction between the chiral modifier and the substrate.

引用

页码：2395 / 2402

页数：8

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