THE WICHTERLE REACTION

被引：4

作者：

HUDLICKY, M

机构：

来源：

COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS | 1993年 / 58卷 / 10期

关键词：

D O I：

10.1135/cccc19932229

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Wichterle reaction is a conversion of vinylic chlorides to ketones by sulfuric acid. Most of the applications are transformations of gamma-chlorocrotyl (3-chloro-2-butenyl) derivatives to 3-oxobutyl derivatives. The ketones thus formed may undergo subsequent reactions in compounds containing reactive centers. Thus intramolecular aldol-type condensations occur in compounds containing carbonyl groups, and Friedel-Crafts-type cyclizations in compounds containing aromatic rings. The reaction can be used as an alternative to Robinson's annelation.

引用

页码：2229 / 2244

页数：16

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[2]

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[3]

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