GAMMA-INTERFERON MODIFIES CD4+ SUBSET EXPRESSION IN MURINE CANDIDIASIS

被引:63
作者
ROMANI, L [1 ]
CENCI, E [1 ]
MENCACCI, A [1 ]
SPACCAPELO, R [1 ]
GROHMANN, U [1 ]
PUCCETTI, P [1 ]
BISTONI, F [1 ]
机构
[1] UNIV PERUGIA, DEPT EXPTL MED & BIOCHEM SCI, I-06100 PERUGIA, ITALY
关键词
D O I
10.1128/IAI.60.11.4950-4952.1992
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A single injection of monoclonal antibody to gamma interferon administered in conjunction with a live Candida albicans yeast cell vaccine resulted in the detection of nonprotective Th2 rather than protective Th1 responses and altered the early expression of interleukin 4 and gamma interferon mRNA in CD4+ cells.
引用
收藏
页码:4950 / 4952
页数:3
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