LOCALIZED PROTON NMR-SPECTROSCOPY OF BRAIN-TUMORS USING SHORT-ECHO TIME STEAM SEQUENCES

被引：112

作者：

FRAHM, J ^{[1
]}

BRUHN, H ^{[1
]}

HANICKE, W ^{[1
]}

MERBOLDT, KD ^{[1
]}

MURSCH, K ^{[1
]}

MARKAKIS, E ^{[1
]}

机构：

[1] UNIV GOTTINGEN,NEUROCHIRURG KLIN,W-3400 GOTTINGEN,GERMANY

来源：

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY | 1991年 / 15卷 / 06期

关键词：

MAGNETIC RESONANCE IMAGING; SPECTROSCOPY; BRAIN; NEOPLASMS; TISSUE CHARACTERIZATION;

D O I：

10.1097/00004728-199111000-00002

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Recent progress in localized proton NMR spectroscopy has been utilized to improve the spatial resolution and the metabolic specificity in a study of 19 patients with intracranial tumors. Selected examples demonstrate that short echo time stimulated echo acquisition mode sequences are able (a) to account for macroscopic tissue heterogeneity by reducing the volume of interest to 2-8 ml and (b) to facilitate a reasonable characterization of tumor metabolism by increasing the number of accessible metabolites. Proton NMR spectra were acquired within measuring times of 6.5 min on a 2.0 T whole-body system using the imaging headcoil.

引用

页码：915 / 922

页数：8

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