CONFIRMATION OF CENTROMERIC FUSION IN 7P/1Q TRANSLOCATION ASSOCIATED WITH MYELODYSPLASTIC SYNDROME

被引：5

作者：

HOO, JJ ^{[1
]}

SZEGO, K ^{[1
]}

JONES, B ^{[1
]}

机构：

[1] RUSH PRESBYTERIAN ST LUKES MED CTR,DEPT PEDIAT,CHICAGO,IL 60612

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 64卷 / 02期

关键词：

D O I：

10.1016/0165-4608(92)90354-B

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Fluorescence in situ hybridization (FISH) using chromosome 1- and chromosome 7-specific centromeric alpha-satellite probes was performed on the bone marrow (BM) cells of a patient with myelodysplastic syndrome (MDS) who had been treated for lymphoma and whose BM karyotype was initially considered to be 46,XY,-7, +der(1)t(1;7)(p11;p11). FISH results suggested the presence of both chromosome 1 and chromosome 7 centromeres in the rearranged chromosome. Thus, the correct karyotype should be written as 46,XY, -7, +der(1;7)(q10;p10).

引用

页码：186 / 188

页数：3

共 14 条

[1] DETERMINATION OF THE BREAKPOINTS OF 1-7 TRANSLOCATIONS IN MYELODYSPLASTIC SYNDROME BY INSITU HYBRIDIZATION USING CHROMOSOME-SPECIFIC ALPHA-SATELLITE DNA FROM HUMAN CHROMOSOME-1 AND CHROMOSOME-7 [J].

ALITALO, T ;

WILLARD, HF ;

DELACHAPELLE, A .

CYTOGENETICS AND CELL GENETICS, 1989, 50 (01) :49-53

[2] AN IDENTICAL TRANSLOCATION BETWEEN CHROMOSOME-1 AND CHROMOSOME-7 IN 3 PATIENTS WITH MYELOFIBROSIS AND MYELOID METAPLASIA [J].

GERAEDTS, JPM ;

OTTOLANDER, GJD ;

PLOEM, JE ;

MUNTINGHE, OG .

BRITISH JOURNAL OF HAEMATOLOGY, 1980, 44 (04) :569-575

[3] TRANSLOCATION (1-7) IN A CASE OF SECONDARY CHRONIC MYELOMONOCYTIC LEUKEMIA [J].

LAI, JL ;

FENAUX, P ;

SAVARY, JB ;

JOUET, JP ;

LEPELLEY, P ;

BAUTERS, F ;

DEMINATTI, M .

CANCER GENETICS AND CYTOGENETICS, 1987, 24 (02) :355-357

[4] COMBINED TRISOMY 1Q AND MONOSOMY 7Q DUE TO TRANSLOCATION 1-7 IN MYELODYSPLASTIC SYNDROMES [J].

MECUCCI, C ;

GHIONE, F ;

TRICOT, G ;

VANDENBERGHE, H .

CANCER GENETICS AND CYTOGENETICS, 1985, 18 (03) :193-197

[5] UNBALANCED 1-7 TRANSLOCATION AND THERAPY-INDUCED HEMATOLOGIC DISORDERS - A POSSIBLE RELATIONSHIP [J].

MORRISONDELAP, SJ ;

KUFFEL, DG ;

DEWALD, GW ;

LETENDRE, L .

AMERICAN JOURNAL OF HEMATOLOGY, 1986, 21 (01) :39-47

[6] DETECTION OF CHROMOSOME-ABERRATIONS IN INTERPHASE TUMOR NUCLEI BY NONRADIOACTIVE IN SITU HYBRIDIZATION [J].

NEDERLOF, PM ;

VANDERFLIER, S ;

RAAP, AK ;

TANKE, HJ ;

VANDERPLOEG, M ;

KORNIPS, F ;

GERAEDTS, JPM .

CANCER GENETICS AND CYTOGENETICS, 1989, 42 (01) :87-98

[7]

PEDERSENBJERGAARD J, 1984, CANCER, V54, P452, DOI 10.1002/1097-0142(19840801)54:3<452::AID-CNCR2820540313>3.0.CO

[8]

2-9

[9] TRANSLOCATION (1-7)(P11-P11) - A NEW MYELOPROLIFERATIVE HEMATOLOGIC ENTITY [J].

SANDBERG, AA ;

MORGAN, R ;

HECHT, BK ;

HECHT, F .

CANCER GENETICS AND CYTOGENETICS, 1985, 18 (03) :199-206

[10] TRANSLOCATION 1-7 IN DYSHEMATOPOIESIS - POSSIBLY INDUCED WITH A NONRANDOM GEOGRAPHIC-DISTRIBUTION [J].

SCHERES, JMJC ;

HUSTINX, TWJ ;

HOLDRINET, RSG ;

GERAEDTS, JPM ;

HAGEMEIJER, A ;

VANDERBLIJPHILIPSEN, M .

CANCER GENETICS AND CYTOGENETICS, 1984, 12 (04) :283-294

← 1 2 →